Skin cell adhesion relies on a network of collagen that attach cells like a spider web, acting as a forces transmitter from the “fibroblasts” to surrounding tissues, causing them to adapt to balance a three-dimensional tensile, all the fibers pull each other, making the cells stronge. The more fibroblasts there are, the stronger the pulling force, resulting in firmer, tighter, and more vibrant skin. Early Boost helps strengthen fibroblasts by increasing the amount and length of dendrites. The test results with Early Boost concentration of 0.15% showed that dendrites of fibroblasts were 2 times longer, allowing proper adhesion between skin cells to be elastic. Therefore, skin is soft, yet strong and looks naturally radiant.

Close-up skin photography reveals clearer skin texture by using the Skin Microscopic Relife technique, which identifies the depth of facial skin. After 14 days, premature wrinkles were significantly reduced, deep grooves and pits were reduced, and pores were tightened.

Lemulia is an innovative formula of Natural Dew Co., Ltd. It is protected by the Department of Intellectual Property as the only exclusive copyright of DEWellness ELIXIR, consisting of key ingredients: Natural Dew, Silver Nano, and Beet Extract.

 

 

From the testing of the solubility of various waters, it was found that dew has the highest solubility, which is 1.05, higher than water from other natural sources, especially mineral water which has the lowest solubility because it contains too many large mineral molecules. And the amazing thing is that even though they have a similar condensation process to coagulate, However, dew has a higher Value destruction than distilled water due to the different molecular structure arrangement, which is smaller and more flexible, so when natural dew is mixed with various nutrients, it occur a coagulation more tightly.

Creams and serums generally have a thick texture due to the various nutrients that are packed in, including substances that stabilize the cream, making it difficult to absorb into the skin. Therefore, there must be a step to enlarge pores before applying to increase the chance of deeper absorption. But with natural dew that has a very high solubility (High Purity Solvent).When the nutrients are dissolved into smaller size and firmly bind to the dew molecules, no matter how deep the dew penetrates, the nutrients will follow deep down too.

 

Repair Complex CLR helps the cells’ functions to increase gradually when exposed to UV radiation, such as in bright sunlight or even when facing a computer screen for a long time. The test found that the extract of Bifida algae can increase the skin cell repair process rapidly, and when the skin is not affected by UV rays, the cell’s function is reduced accordingly. This means that as soon as skin cells are injured or experience any abnormalities, whether it be inflammation or irritation, they are ready to repair and restore immediately.

Squalane controls the expression of cytokines which stimulate inflammation in human monocytes and neutrophils that treated with lipopolysaccharide (LPS), an anti-inflammatory and antibacterial agent, compared with Squalane for 18 hours. After that, The mRNA levels of different cytokines including TNF-, IL-1B, IL-6, IL-10 and IFN-Y were measured the level of inflammation. Squalane was found to reduce the level of inflammation with the success rate being depending on higher concentrations ,providing better results.

 

Corneocytes Corneocytes or dead skin cells that no longer have any metabolic processes. The main function of the corneocytes is to protect the skin from external stimuli. However, you have to be aware of the accumulation of pollutants such as dust, chemicals, and germs which may remain for too long and be absorbed into the skin. If it is not taken care of regularly, on the contrary, we can use our dead skin cells to maintain moisture in the deeper layers of the skin, which also helps the skin cells to exfoliate more naturally.

Squalane controls the expression of cytokines which stimulate inflammation in human monocytes and neutrophils that treated with lipopolysaccharide (LPS), an anti-inflammatory and antibacterial agent, compared with Squalane for 18 hours. After that, The mRNA levels of different cytokines including TNF-, IL-1B, IL-6, IL-10 and IFN-Y were measured the level of inflammation. Squalane was found to reduce the level of inflammation with the success rate being depending on higher concentrations providing better results.

 

“Gnenecare“ Its main function is to moisturize the skin by focusing on the exchange of nutrients at the cellular level. It depends on the different concentrations across the cell membrane (Osmolyte), which is a zwitterionic molecule, i.e. a dipolar molecule, so it is a neutral molecule with both positive and negative charges. It can flexibly circulate nutrients and moisture to the skin, resulting in smooth, soft, hydrated, and healthy skin.

Betaine is effective in improving the integrity of skin cell connections. It increases the elasticity of our skin by making skin cells attach together more tightly, making the skin stronger, firmer, and more radiant and smoother.

 

In test of the moisture rate of Advance Moisture Complex (AMC) compared to Hyaluronic Acid, a highly effective moisturizer, it was found that AMC has a moisture rate that is 4 times higher.

The AMC test results with samples showed that the Measuring moisture content was 21% higher. It shows its effectiveness in increasing moisture deep into the skin cells and, importantly, retaining moisture for up to 5 times longer than usual.t

 

Irritation from cleaning products, which is caused by surfactants such as Sodium Lauryl Sulfate (SLS), which is a safe substance but often causes irritated and makes the skin feel dry and tight by Comthing SGS, which is rich in natural extracts, can relieve irritation from SLS by up to 54.3%.

Enlarged image of a group of skin cell tissues that are irritated by a cleaning product. It shows signs of inflammation with enlarged capillaries, indicating skin abnormalities and causing a burning, itching, swelling, redness, dryness, and discomfort to the skin. However, when using Comthing SGS at 10% after cleaning the skin, it can effectively reduce various irritations. Abnormal tissue symptoms return to normal within just 5 minutes.

 

Beta-glucan stimulates the body’s immune system by connecting to macrophages, a type of white blood cell that detects bacteria, viruses, and other pathogens. When stimulated with beta-glucan, macrophages are more efficient at detecting and destroying pathogens. After ingesting pathogens through a process called phagocytosis, macrophages will alert the body to the presence of the pathogen. Research has shown that macrophages which is supplemented with beta-glucan can enhance the body’s overall immune system.

A 1997 study by Portera et al. It was revealed that after injecting water-soluble phosphate glucan into the postoperative wounds of rats’ backs and intestines, not only did the elasticity of the tissue surrounding the surgical site increase, but the surrounding collagen protein was also stimulated to produce more. Therefore, it is hypothesized that water-soluble beta-glucan can indirectly stimulate macrophages to increase collagen protein production, which results in improved skin rejuvenation outcomes.This hypothesis was further substantiated by a long-term study, which confirmed that when fibroblasts were stimulated with beta-D-glucan, the immune response around the tissue was significantly enhanced.

 

A comparison of the astringent properties of four lotions: a placebo, a lotion containing 3% LARICYL LS 8865, and two standard lotions: a lotion containing 3% Hamamelis extract and a lotion containing 0.1% zinc paraphenol sulfonate. The results of 40 tests show its effectiveness in reducing oiliness by reducing the function of the sebaceous glands (Sebum).

Comparative results of the humidifying efficiency of gels containing LARICYL LS 8865 (2% and 5%) with the efficiency
of placebo gels by placing the epidermis samples in a temperature and humidity controlled room to measure the
electrical conductivity.

 

Results of the skin penetration study using abdominal tissue without subcutaneous fat, applied with 5% or 50% SymGlucan solution
once. After 8 hours, the tissues were thinly sliced, stained with Calcofluor White, and examined under a fluorescence microscope.
The results showed that SymGlucan penetrated deeply into the epidermis and dermis.

Results of an 8-week light-activated clinical study using facial treatments on 27 subjects, randomized to twice daily use of SymGlucan
10% gel vs. placebo. Skin elasticity measurements using the Cutometer showed a significant reduction in skin wrinkles. Close-up
photographs of the left and right sides of the face show a reduction in wrinkles and fine lines. Image analysis of the silicone implant
from the outer corner of the eye shows an effective smoothness on the skin.

 

 

Results from 207 users tested with Zemea propanediol, propylene glycol or a control at pH 7. Irritation response was
measured at different concentrations. The results showed that Zemea propanediol did not cause irritation, but propanediol
did cause skin irritation when used at a concentration of 25%, with nearly a quarter of users experiencing more severe
irritation at a concentration of 75%.

The moisturizing efficacy of facial emulsions containing 5% humectant was measured using a Corneometer CM 825
(Courage & Khazaka) to measure skin moisturizing effect. The test results showed that Zemea Propanediol was more
effective than butylene glycol and propylene glycol in moisturizing the skin throughout the test period.

 

In a comparative test of different emulsions, the lotion containing Zemea Propanediol scored higher than the other samples
in all characteristics, which makes Divine Boost’s texture soft and gentle on all skin types

 

Tape stripping technique test by applying a piece of tape to the upper skin and peeling it off continuously for about 20
times. The weight of the tape was measured before and after doing this to study the absorption through the skin from
the outside.
Peeling off the tape to determine the weight of the stratum corneum and created a model of acute skin barrier
disruption by measuring the recovery from Transepidermal Water Loss (TEWL) and the thickness of the skin barrier
using ceramides. The higher amount of the ceramide, the faster the TEWL recovery. The skin lipids are thicker when
using 1.0% ceramide NP, strengthen the skin barrier to work better.

From the collection of data from the stratum comeum layer, it was found that the level of ceramide in the stratum
comeum layer gradually decreases with increasing age. This has a clear effect on the physical appearance of the skin,
such as thinner skin, less fibroblasts, increased keratin, and much less and low quality collagen, resulting in a
progressive decrease in skin elasticity.  

Olivem 1000 is 145% more hydrating than cetearyl alcohol, which is often used with cetearyl glucoside, and more than
polyglyceryl-3 methylglucose distearate, a widely used humectant, and is a Substance in the category of similar result
but more hydrating ingredient up to 145%.

The important key missing piece for a good moisturizer is consistency, which is the strong point of DEWellness ELIXIR,
which focuses on moisture, the key to healthy skin throughout the day . Moisturisers are very effective initially but
quickly lose their effectiveness after that. Unlike Olivem 1000, which maintains moisture for up to 45% longer, even
under extreme skin conditions.

 

From the cell membrane integrity test, damaged cells were treated with Olivem 1000 by measuring the absorbance of
light to determine the damage to the cell membrane, Olivem 1000 was able to heal the injured cells and reduce the
accumulated stress almost 2 times better.

Data from a corneometer showed that Hydrovance was as effective as glycerin in moisturizing the skin, with peak
moisture levels at 3 weeks after use.

Immediately after application, the evaluation of oil absorption, stickiness and residue amount showed that Hydrovance
was significantly more effective than glycerin and better than or equal to other tested moisturizers.

 

Corneometer test showed a significant difference after just 1 hour of MARSturizer application. Skin was fully hydrated
and the rate of transepidermal water loss (TEWL) was reduced, keeping skin fresh for longer.

The regeneration process is effective immediately after use for only 48 hours. The damaged Nitrogenous Base is
restored to normal, resulting in the skin cells functioning well again.